PainExam News
A Place for Board Certified and Board Eligible Pain Management Anesthesiologists to share concerns and important
topics relevant to the Practice of Pain.
Fentanyl Metabolism and excretion It interacts with opiate receptors decreasing pain impulse transmission at the spinal cord level and higher in the CNS. Fentanyl is a potent ยต-opiate receptor agonist. Also causes peripheral vasodilation increasing venous capacitance and decreases ...
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Propofol Metabolism and excretion Propofol is highly protein-bound in vivo and is metabolised by conjugation in the liver. (1) The half life of elimination of propofol has been estimated at between 2 and 24 hours. Its duration of clinical effect is much shorter, because propofol...
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